Subjects of MSc theses realized in the Department

  • Isolation and biochemical characterisation of proteolytic enzymes and their natural protein inhibitors of bacterial origin.
  • Protein expression in heterological bacterial system.
  • Cloning, expression and purification of recombinant proteins.
  • Protein folding processes.
  • Antibacterial peptides: isolation, purification, sequencing and biochemical characterisation.
  • Bacteriocins: isolation, purification, sequencing and biochemical characterisation.
  • New techniques in protein and peptide chemistry.
  • Studies on interaction of MDM2 and MDM4 proteins with p53 – in close cooperation with Dr. Tad Holak from Max-Planck Institute of Biochemistry in Munich.
  • Identification and kinetic characterization of enzymes involved in plant thiamine biosynthesis.
  • Structural characterization of thiamine biosynthesis enzymes with site-direct mutagenesis.
  • Interaction of the contact system proteins, kininogen, prekallikrein and factor XII with the surface of selected Candida species. 
  • Kinin generation by secreted proteinases from Candida spp. 
  • Biochemical applications of biologically active substance immobilized in silicon carbide nanoparticles.
  • Mechanism of kinin generation in tissue cell models.
  • Expression of genes and proteins involved in the regulation of inflammation, especially in relation to the kinin generation system.